The Impact of Generics on Affordability

Posted on 19th January 2024

Generic medicines play an indispensable role in ensuring the financial and operational sustainability of the NHS. NHS doctors issue over 1 billion medicine prescriptions annually to treat British patients, with generic medicines constituting 75% of all dispensed treatments. This makes the UK the largest prescriber of generics across all European countries.

These cheaper generic alternatives contain pharmacologically identical active ingredients to the original higher-priced brand-name versions after initial patent protections expire. Extensive medical studies confirm that carefully regulated generics provide clinically equivalent benefits to their brand-name counterparts.

However, the significantly lower prices of generics yield massive cost savings that translate into vastly improved system capacity. An independent report by economic analysis firm Oxera highlights how the existing framework in the UK generics market encourages fierce price competition amongst manufacturers. This creates greater medicine choice for prescribers, substantially reduced pricing for cash-strapped NHS trusts, and enhanced supply reliability even for low-margin treatments.

The cost savings unlocked by generics also incentivise pharmaceutical research investments by enabling companies to profit from new molecular entity discoveries for a limited 7–10-year period before affordable generic alternatives become available. Typically, generic prices fall by 70% within the first 6 months after entering the market post patent expiry, then drop a further 80-90% over the next 4 years as more manufacturers enter the now de-risked space.

This price erosion allows the resource-constrained NHS to treat more patients for the same cost. Such efficiency and scalability will remain crucial as increasingly advanced medicines emerge to treat the UK’s ageing population.

Developing policies that balance private-sector innovation with public-sector accessibility will be vital to create an optimised, patient-centric health system.
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